If there is a King of Comedy right now in Hollywood, that would be Judd Apatow. I have a list here of a dozen comedies he has produced and/or directed just in the last five years, and I left out the titles I didn't like. He has been writing since he was a kid, producing since he was 23, and then he directed "The 40-Year-Old Virgin" (2005) and "Knocked Up" (2007) himself. He is only 41. I think he's hitting his stride.